Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease
نویسندگان
چکیده
منابع مشابه
Neonatal Presentation of Unremitting Inflammatory Bowel Disease
Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...
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inflammatory bowel disease (ibd) is a chronic relapsing, idiopathic disorder of the gastrointestinal tract of an unknown etiology. ulcerative colitis (uc) and crohn's disease (cd) have become important health problems.â current medical therapy of ibd has advanced dramatically with the introduction of new biologic therapies in addition to the optimization of conventional therapies that include ...
متن کاملEvaluation of a nanosuspension formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers
This study aimed to determine the aerosolization behavior of a nanodispersion of budesonide, prepared using microfluidic reactors. The size and morphology of budesonide nanoparticles were characterized by photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM). Processing/formulation parameters for formation of the nanoparticles were studied to determine their effects o...
متن کاملEvaluation of a nanosuspension formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers
This study aimed to determine the aerosolization behavior of a nanodispersion of budesonide, prepared using microfluidic reactors. The size and morphology of budesonide nanoparticles were characterized by photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM). Processing/formulation parameters for formation of the nanoparticles were studied to determine their effects o...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2018
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2018.09.005